F9 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human F9 wild-type allele is located within Xq27.1-q27.2 and is approximately 33 kb in length. This allele, which encodes coagulation factor IX protein, plays a role in the intrinsic blood coagulation cascade. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency. This is a recessive X-linked disorder, also called hemophilia B or Christmas disease.

**Synonyms:** - Christmas Disease Gene - Coagulation Factor IX (Plasma Thromboplastic Component, Christmas Disease, Hemophilia B) Gene - Coagulation Factor IX wt Allele - FIX - HEMB - Hemophilia B Gene - P19 - PTC - RP6-88D7.1 - THPH8