VWF wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human VWF wild-type allele is located in the vicinity of 12p13.31 and is approximately 176 kb in length. This allele, which encodes von Willebrand factor protein, plays a role in factor transport, platelet-vessel wall mediation, and coagulation. Mutations in this gene or deficiencies in this protein result in von Willebrand disease.

**Synonyms:** - F8VWF - FVIII-VWF - VWD - Von Willebrand Factor wt Allele - von Willebrand Disease Gene