PIM1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PIM1 wild-type allele is located in the vicinity of 6p21.2 and is approximately 5 kb in length. This allele, which encodes proto-oncogene serine/threonine-protein kinase Pim-1 protein, plays a role in the proliferation and survival of blood cells. The PIM1 gene is overexpressed in hematopoietic malignancies such as chronic myeloid leukemia and acute lymphocytic leukemia.

**Synonyms:** - PIM - PIM-1 Oncogene wt Allele - Pim-1 Oncogene (Proviral Integration Site 1) Gene - Pim-1 Proto-Oncogene, Serine/Threonine Kinase wt Allele - Proto-Oncogene Serine/Threonine-Protein Kinase Pim-1 Gene - Provirus Insertion Site Gene-1