PRKCA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PRKCA wild-type allele is located in the vicinity of 17q24.2 and is approximately 508 kb in length. This allele, which encodes protein kinase C alpha type protein, is involved in the phosphorylation of diverse protein substrates in response to activation by calcium or the second messenger diacylglycerol. The PRKCA gene is overexpressed in certain types of cancer such as breast tumors, glioblastomas, pituitary tumors and thyroid neoplasms.

**Synonyms:** - AAG6 - Aging-Associated Gene 6 - PKC-alpha - PKCA - PKCalpha - PRKACA - Protein Kinase C Alpha wt Allele - Protein Kinase C, Alpha Gene