PTCH2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PTCH2 wild-type allele is located within 1p33-p34 and is approximately 21 kb in length. This allele, which encodes protein patched homolog 2 protein, is involved in the formation of embryonic structures. Aberrant allelic expression has been linked to medulloblastoma and basal cell carcinoma, suggesting that variants play a role in the development of some tumors.

**Synonyms:** - PTC2 - Patched (Drosophila) Homolog 2 Gene - Patched 2 wt Allele - Patched Homolog 2 (Drosophila) Gene - Patched Homolog 2 Gene - Patched, Drosophila, Homolog of, 2 Gene - UNQ560/PRO1121/PRO57079