PURA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PURA wild-type allele is located within 5q31 and is approximately 3 kb in length. This allele, which encodes transcriptional activator protein Pur-alpha, is involved in both DNA replication and transcription. The deletion of this gene has been implicated in myelodysplastic syndrome and acute myelogenous leukemia.

**Synonyms:** - PUR-Alpha - PUR1 - PURALPHA - Purine-Rich Element Binding Protein A wt Allele