Hereditary Leiomyomatosis and Renal Cell Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** An autosomal dominant inherited syndrome caused by germline mutations in the FH gene. It is characterized by predisposition to renal cell carcinoma, leiomyomas of the skin and uterus, and leiomyosarcoma of the uterus.

**Synonyms:** - FH Deficiency - HLRCC - HLRCC - Hereditary Leiomyomatosis and Renal Cell Cancer - Hereditary Leiomyomatosis and Renal Cell Cancer - Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome - Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome - Hereditary leiomyomatosis & RCC-associated renal cell carcinoma - hereditary leiomyomatosis and renal cell cancer syndrome