RIPK2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human RIPK2 wild-type allele is located within 8q21 and is approximately 33 kb in length. This allele, which encodes receptor-interacting serine/threonine-protein kinase 2 protein, plays a role in promotion of apoptosis, activation of the transcription factor NF-kappa-B, and signaling involved in both the innate and adaptive immune response pathways.

**Synonyms:** - CARD3 - CARDIAK - RICK - RIP2 - Receptor-Interacting Serine-Threonine Kinase 2 wt Allele