CSF2RB wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CSF2RB wild-type allele is located in the vicinity of 22q13.1 and is approximately 17 kb in length. This allele, which encodes cytokine receptor common beta chain protein, is involved in signal transduction. Mutations in the gene that produce variant alleles are associated with the pathogenesis of that myeloproliferative disorder and protein alveolar proteinosis.

**Synonyms:** - CD131 - CDw131 - CITF22-45C1.4 - Colony Stimulating Factor 2 Receptor, Beta Gene - Colony Stimulating Factor 2 Receptor, Beta, Low-Affinity (Granulocyte-Macrophage) wt Allele - Granulocyte-Macrophage Colony-Stimulating Factor Receptor, Beta Gene - IL3RB - IL5RB - Interleukin 3 Receptor/Granulocyte-Macrophage Colony Stimulating Factor 3 Receptor, Beta (High Affinity) Gene - SMDP5