IL4R wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IL4R wild-type allele is located within 16p11.2-12.1 and is approximately 35 kb in length. This allele, which encodes interleukin-4 receptor subunit alpha protein, plays a role in Th2 cell differentiation, immunoglobulin E (IgE) production and cellular proliferation regulation. Allelic variants are associated with atopy. This condition can be typified as allergic rhinitis, sinusitus, asthma, or eczema.

**Synonyms:** - 582J2.1 - CD124 - IL-4RA - IL4RA - Interleukin 4 Receptor wt Allele - Interleukin 4 Receptor, Alpha Gene