ERBB3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ERBB3 wild-type allele is located within 12q13 and is approximately 23 kb in length. This allele, which encodes receptor tyrosine-protein kinase erbB-3 protein, is involved in the regulation of celullar proliferation and differentiation. Amplification or overexpression of this gene, has been documented in several solid tumors and cancers, including prostate, bladder, and breast.

**Synonyms:** - EGF Receptor 3 Gene - Erb-B2 Receptor Tyrosine Kinase 3 wt Allele - ErbB-3 - FERLK - HER3 - LCCS2 - MDA-BF-1 - V-ERB-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 (Avian) Gene - V-ERB-B2 Erythroblastic Leukemia Viral Oncogene Homolog 3 Gene - V-Erb-A Erythroblastic Leukemia Viral Oncogene Homolog 4 Gene - VSCN1 - c-erbB-3 - c-erbB3 - erbB3-S - p180-ErbB3 - p45-sErbB3 - p85-sErbB3