SLPI wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SLPI wild-type allele is located within 20q12 and is approximately 2 kb in length. This allele, which encodes antileukoproteinase 1 protein, plays a role in the protection of epithelial tissues from degradation by serine proteases. The SLPI gene is overexpressed in certain types of cancer such as non-small cell lung carcinomas and ovarian carcinomas.

**Synonyms:** - ALK1 - ALP - BLPI - HUSI - HUSI-I - SLPIa - Secretory Leukocyte Protease Inhibitor (Antileukoproteinase) wt Allele