SET wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SET wild-type allele is located within 9q34 and is approximately 12 kb in length. This allele, which encodes protein SET, plays a role in histone binding, nucleosome assembly, transcription and negative regulation of apoptosis. Translocation of the SET gene is associated with acute undifferentiated leukemia.

**Synonyms:** - 2PP2A - I2PP2A - IGAAD - IPP2A2 - MRD58 - PHAPII - Protein Phosphatase Type 2A Inhibitor - SET Nuclear Proto-Oncogene wt Allele - SET Translocation (Myeloid Leukemia-Associated) Gene - TAF-I - TAF-IBETA - Template-Activating Factor-I, Chromatin Remodelling Factor Gene