BDNF wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human BDNF wild-type allele is located in the vicinity of 11p14.1 and is approximately 67 kb in length. This allele, which encodes brain-derived neurotrophic factor protein, is involved in both stress response regulation and in the survival of striatal neurons. Expression of the allele is decreased in both Alzheimer's and Huntington disease.

**Synonyms:** - ANON2 - BULN2 - Brain Derived Neurotrophic Factor wt Allele - Brain-Derived Neurotrophic Factor Gene - MGC34632 - Neurotrophin Gene