DRD2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DRD2 wild-type allele is located within 11q23 and is approximately 66 kb in length. This allele, which encodes D(2) dopamine receptor protein, plays a role in the inhibition of adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia and allelic variant mutants are associated with schizophrenia.

**Synonyms:** - D(2) Dopamine Receptor Gene - D2DR - D2DR Gene - D2R - D2R Gene - Dopamine Receptor D2 wt Allele