DRD5 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DRD5 wild-type allele is located in the vicinity of 4p16.1 and is approximately 2 kb in length. This allele, which encodes D(1B) dopamine receptor protein, plays a role in the stimulation of adenylate cyclase activity and intracellular accumulation of cAMP. Defects in DRD5 are a cause of blepharospasm, a primary focal dystonia affecting the orbicularis oculi muscles.

**Synonyms:** - D(1B) Dopamine Receptor Gene - D(5) Dopamine Receptor Gene - D1beta Dopamine Receptor Gene - DBDR Gene - DRD1B Gene - DRD1L2 Gene - Dopamine Receptor D1B Gene - Dopamine Receptor D5 wt Allele