SMO wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SMO wild-type allele is located in the vicinity of 7q32.1 and is approximately 25 kb in length. This allele, which encodes protein smoothened, is involved in G protein-coupled receptor signal transduction in the sonic hedgehog signaling pathway.

**Synonyms:** - CRJS - FZD11 - Frizzled Family Member 11 Gene - Gx - PHLS - SMOH - Smoothened (Drosophila) Homolog Gene - Smoothened Homolog (Drosophila) Gene - Smoothened, Drosophila, Homolog Gene - Smoothened, Frizzled Class Receptor wt Allele - Smoothened, Frizzled Family Receptor Gene - Smoothened, Seven Transmembrane Spanning Receptor Gene