NRG1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NRG1 wild-type allele is located within 8p21-p12 and is approximately 1,124 kb in length. This allele, which encodes pro-neuregulin-1, membrane-bound isoform protein, is involved in the compositional regulation of neurotransmitter receptors in maturing synapses in the brain, proliferation and differentiation.

**Synonyms:** - ARIA - Acetylcholine Receptor Inducing Activity, Chick, Homolog of Gene - GGF - GGF2 - HGL - HRG - HRG1 - HRGA - Heregulin Gene - Heregulin, Alpha (45kD, ERBB2 p185-Activator) Gene - Heregulin, Alpha Gene - MST131 - MSTP131 - NDF - NEU Differentiation Factor Gene - Neuregulin 1 wt Allele - SMDF