PDGFB wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PDGFB wild-type allele is located in the vicinity of 22q13.1 and is approximately 22 kb in length. This allele, which encodes platelet-derived growth factor subunit B protein, is involved in mitogenesis for mesenchymal cells. Mutations in the gene produce allelic variants that are associated with meningioma.

**Synonyms:** - IBGC5 - LL22NC03-10C3.2 - Oncogene SIS Gene - PDGF-2 - PDGF2 - Platelet Derived Growth Factor Subunit B wt Allele - Platelet-Derived Growth Factor Beta Polypeptide (Simian Sarcoma Viral (v-sis) Oncogene Homolog) Gene - Platelet-Derived Growth Factor Beta Polypeptide Gene - Platelet-Derived Growth Factor, Beta Polypeptide (Oncogene SIS) Gene - SIS - SIS Gene - SSV - Simian Sarcoma Viral Oncogene Homolog Gene - c-sis - v-SIS Homolog