TNF wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TNF wild-type allele is located in the vicinity of 6p21.3 and is approximately 3 kb in length. This allele, which encodes tumor necrosis factor protein, is involved in a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Aberrant alleles have been associated with a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.

**Synonyms:** - DIF - IMD127 - TNF A - TNF Superfamily, Member 2 Gene - TNF, Macrophage-Derived Gene - TNF, Monocyte-Derived Gene - TNF-alpha - TNFA - TNFSF2 - TNLG1F - Tumor Necrosis Factor (TNF Superfamily, Member 2) Gene - Tumor Necrosis Factor wt Allele - Tumor Necrosis Factor, Alpha Gene - Tumor Necrosis Factor-Alpha (Macrophage-Derived) Gene