NGFR wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human NGFR wild-type allele is located within 17q21-q22 and is approximately 20 kb in length. This allele, which encodes tumor necrosis factor receptor superfamily member 16 protein, plays a role in several biological process through signal transduction. The allele is involved in neuronal growth and apoptosis through nuclear factor kappa-B modulation.

**Synonyms:** - CD271 - Gp80-LNGFR - Nerve Growth Factor Receptor (TNFR Superfamily, Member 16) Gene - Nerve Growth Factor Receptor wt Allele - TNFR Superfamily, Member 16 Gene - TNFRSF16 - Tumor Necrosis Factor Receptor Superfamily, Member 16 Gene - p75(NTR) - p75NTR