TGFBR2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TGFBR2 wild-type allele is located within 3p22 and is approximately 88 kb in length. This allele, which encodes TGF-beta receptor type-2 protein, plays a role in transcriptional regulation and cellular proliferation control. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors.

**Synonyms:** - AAT3 - FAA3 - HNPCC6 - LDS1B - LDS2 - LDS2B - MFS2 - RIIC - TAAD2 - TBR-ii - TBRII - TGF-Beta Receptor Type IIB Gene - TGFBR2 - TGFR-2 - TGFbeta-RII - Transforming Growth Factor Beta Receptor 2 wt Allele - Transforming Growth Factor Beta Receptor II Gene - Transforming Growth Factor, Beta Receptor II (70/80kDa) Gene - Transforming Growth Factor, Beta Receptor II Beta Gene - tbetaR-II