KIT wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KIT wild-type allele is located within 4q11-q12 and is approximately 83 kb in length. This allele, which encodes mast/stem cell growth factor receptor protein, plays a role in the mediation of transmembrane-receptor interactions. Mutations in the gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism.

**Synonyms:** - C-KIT - CD117 - KIT - SCF Receptor Gene - SCFR - Stem Cell Factor Receptor Gene - V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog wt Allele