CD3G wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CD3G wild-type allele is located within 11q23 and is approximately 9 kb in length. This allele, which encodes T-cell surface glycoprotein CD3 gamma chain protein, plays a role in signal transduction in T cells and is involved in the transition of immature thymocytes to mature CD4+ or CD8+ T cells. Certain allelic variants of the CD3G gene are associated with T cell immunodeficiency.

**Synonyms:** - CD3G Antigen, Gamma Polypeptide (TiT3 Complex) wt Allele - T3G