GCLM wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GCLM wild-type allele is located in the vicinity of 1p22.1 and is approximately 21 kb in length. This allele, which encodes glutamate-cysteine ligase regulatory subunit protein, plays a role in glutathione biosynthesis. An allelic variant of the GCLM gene is associated with susceptibility to myocardial infarction.

**Synonyms:** - GLCLR - Gamma-Glutamylcysteine Synthetase, Regulatory Subunit Gene - Glutamate-Cysteine Ligase (Gamma-Glutamylcysteine Synthetase), Regulatory (30.8kD) Gene - Glutamate-Cysteine Ligase Modifier Subunit wt Allele - Glutamate-Cysteine Ligase, Modifier Subunit Gene - Glutamate-Cysteine Ligase, Regulatory Gene - RP4-561L24.2