IL12RB1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human IL12RB1 wild-type allele is located in the vicinity of 19p13.1 and is approximately 74 kb in length. This allele, which encodes interleukin-12 receptor beta-1 chain protein, is involved in IL12 signal transduction. Heritable defects in the IL12RB1 gene are a cause of susceptibility to mycobacterial disease.

**Synonyms:** - CD212 - IL-12R-BETA1 - IL12R - IL12RB - Interleukin 12 Receptor, Beta 1 wt Allele