DOCK1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human DOCK1 wild-type allele is located within 10q26.13-q26.3 and is approximately 557 kb in length. This allele, which encodes dedicator of cytokinesis protein 1, plays a role in cytoskeletal remodeling necessary for both cell motility/migration and phagocytosis of apoptotic cells.

**Synonyms:** - DOCK, 180-kD Gene - DOCK180 Gene - Dedicator of Cyto-Kinesis 1 Gene - Dedicator of Cytokinesis 1 wt Allele - Downstream of CRK-Binding Protein, 180-kD Gene