HMGB1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human HMGB1 wild-type allele is located within 13q12 and is approximately 159 kb in length. This allele, which encodes high mobility group protein B1, is involved in a number of DNA-related subcellular processes such as initiation of transcription, DNA repair and DNA recombination. Expression of the HMGB1 gene is associated with inflammation resulting in both lethal conditions (e.g., endotoxemia, sepsis) and diseases such as arthritis.

**Synonyms:** - Amphoterin Gene - Chromosomal Protein, Nonhistone, HMG1 Gene - HMG-1 Gene - HMG1 Gene - HMG3 Gene - High Mobility Group Protein 1 Gene - High-Mobility Group (Nonhistone Chromosomal) Protein 1 Gene - High-Mobility Group Box 1 wt Allele - Nonhistone Chromosomal Protein HGM1 Gene - SBP-1 Gene - Sulfoglucuronyl Carbohydrate Binding Protein Gene