PHB1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PHB1 wild-type allele is located in the vicinity of 17q21.33 and is approximately 11 kb in length. This allele, which encodes prohibitin 1 protein, plays a role in the repression of cellular proliferation. Mutations in this gene have been linked to sporadic breast cancer.

**Synonyms:** - HEL-215 - HEL-S-54e - PHB - PHB wt Allele - Prohibitin 1 wt Allele - Prohibitin Gene