TFF1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TFF1 wild-type allele is located in the vicinity of 21q23.1 and is approximately 4 kb in length. This allele, which encodes trefoil factor 1 protein, is involved in gastrointestinal mucosa stabilization. Wild type allele dysfunction, including altered expression, deletion, and/or mutation, is observed frequently in human gastric carcinomas.

**Synonyms:** - BCEI - Breast Cancer Estrogen-Inducible Sequence Gene - Breast Cancer, Estrogen-Inducible Sequence Expressed In Gene - D21S21 - HP1.A - HPS2 - Trefoil Factor 1 (Breast Cancer, Estrogen-Inducible Sequence Expressed In) Gene - Trefoil Factor 1 wt Allele - pNR-2 - pS2