PAX5 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PAX5 wild-type allele is located in the vicinity of 9p13 and is approximately 201 kb in length. This allele, which encodes paired box gene Pax-5 protein, is involved in transcriptional activation during B-cell differentiation, neural development and spermatogenesis. In some lymphomas, the expression of the wild-type allele is elevated as a result of a translocation t(9;14)(p13;q32).

**Synonyms:** - ALL3 - BSAP - PAX5 Beta - PAX5 Beta Gene - Paired Box 5 wt Allele - Paired Box Gene 5 - Paired Box Gene 5 (B-Cell Lineage Specific Activator) Gene - Paired Box Homeotic Gene 5