STAT3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human STAT3 wild-type allele is located in the vicinity of 17q21 and is approximately 75 kb in length. This allele, which encodes signal transducer and activator of transcription 3 protein, plays a role in cellular growth, apoptosis and transcriptional enhancement that is mediated by both cytokines and growth factors.

**Synonyms:** - ADMIO - ADMIO1 - APRF - HIES - Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) Gene - Signal Transducer and Activator of Transcription 3 wt Allele