ERBB4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ERBB4 wild-type allele is located within 2q33.3-q34 and is approximately 1156 kb in length. This allele, which encodes receptor tyrosine-protein kinase erbB-4 protein, is involved in the regulation of mitogenesis and differentiation. Mutations in this gene and overexpression are associated with several cancers, including breast cancer.

**Synonyms:** - ALS19 - ERBB-4 - Erb-B2 Receptor Tyrosine Kinase 4 wt Allele - HER-4 - HER4 - NDF/Heregulin Receptor Gene - V-ERB-A Erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) Gene - V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 4 Gene - p180erbB4