KDR wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KDR wild-type allele is located within 4q11-q12 and is approximately 47 kb in length. This allele, which encodes vascular endothelial growth factor receptor 2 protein, plays a role in vascular development, regulation of vascular permeability and VEGF signal transduction.

**Synonyms:** - CD309 - FLK1 - Kinase Insert Domain Receptor (A Type III Receptor Tyrosine Kinase) Gene - Kinase Insert Domain Receptor wt Allele - Tyrosine Kinase Growth Factor Receptor FLK1, Mouse, Homolog of Gene - VEGFR - VEGFR2