Ropivacaine Hydrochloride

**Semantic type:** Pharmacologic Substance

**Definition:** The hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity. Ropivacaine binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions and resulting in a stabilization of the neuronal membrane and inhibition of depolarization; nerve impulse generation and propagation are blocked, resulting in a reversible loss of sensation.

**Synonyms:** - (S)-(-)-1-Propylpiperidine-2-carboxylic acid (2,6-dimethylphenyl)amide Hydrochloride Monohydrate - Naropin - Naropin - ROPIVACAINE HYDROCHLORIDE - Ropivacaine Hydrochloride Monohydrate - S-(-)-1-propyl-2,6-pipecoloxylidide Hydrochloride Monohydrate - ropivacaine hydrochloride