TEK wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TEK wild-type allele is located within 9p21 and is approximately 121 kb in length. This allele, which encodes angiopoietin-1 receptor protein, is involved in angiogenesis, endothelial cell proliferation and differentiation and endothelial cell patterning during vascular morphogenesis. Defects and deficiencies in TEK are associated with venous malformations.

**Synonyms:** - CD202b - GLC3E - Protein Receptor Tyrosine Kinase, Epithelial-Specific, TIE-2 Gene - TEK - TEK Receptor Tyrosine Kinase wt Allele - TEK Tyrosine Kinase, Endothelial (Venous Malformations, Multiple Cutaneous and Mucosal) Gene - TEK Tyrosine Kinase, Endothelial Gene - TIE-2 - TIE2 - VMCM - VMCM1