ZAP70 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ZAP70 wild-type allele is located within 2q12 and is approximately 26 kb in length. This allele, which encodes ZAP70 protein, plays a role in the mediation of signal transduction involving cellular effectors in lymphocyte activation. ZAP70 ab gene aberrations cause Selective T-Cell Defect disease.

**Synonyms:** - SRK - STD - ZAP-70 - ZAP-70 Gene - ZAP70 - Zeta-Chain (TCR) Associated Protein Kinase 70kDa wt Allele