TFR2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TFR2 wild-type allele is located within 7q22 and is approximately 21 kb in length. This allele, which encodes transferrin receptor protein 2, plays a role in the mediation of transferrin-bound iron cellular transport. TFR2 defects are associated with hereditary hemochromatosis type III.

**Synonyms:** - HFE3 - TFRC2 - Transferrin Receptor 2 wt Allele