ABCG2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ABCG2 wild-type allele is located within 4q22 and is approximately 67 kb in length. This allele, which encodesbroad substrate specificity ATP-binding cassette transporter ABCG2 protein, plays a role in transmembrane transport and transcriptional regulation. The allele is thought to play a role in cellular defense and aberrations are thought to play a role in tumor multidrug resistance.

**Synonyms:** - ABC15 - ABCG2 - ABCP - ATP-Binding Cassette Transporter, Placenta-Specific Gene - ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (Junior Blood Group) wt Allele - ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 Gene - ATP-Binding Cassette, Subfamily G, Member 2 Gene - BCRP - BCRP1 - BMDP - CD338 - CDw338 - EST157481 - GOUT1 - MRX - MXR - MXR1 - UAQTL1