SLC5A5 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SLC5A5 wild-type allele is located within 19p13.2-p12 and is approximately 22 kb in length. This allele, which encodes sodium/iodide cotransporter protein, plays a role in the mediation of iodide transport into the thyroid. Mutations in the gene are linked to hypothyroidism due to an iodide transport defect.

**Synonyms:** - NIS Gene - SLC5A5 - Sodium-Iodide Symporter Gene - Solute Carrier Family 5 (Sodium Iodide Symporter), Member 5 Gene - Solute Carrier Family 5 (Sodium/Iodide Cotransporter), Member 5 wt Allele - TDH1