TAP1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TAP1 wild-type allele is located in the vicinity of 6p21.3 and is approximately 9 kb in length. This allele, which encodes antigen peptide transporter 1 protein, is involved in the presentation of antigen fragments to major histocompatibiltiy complex class I proteins. Mutations in the gene are associated with with ankylosing spondylitis, insulin-dependent diabetes mellitus, type I bare lymphocyte syndrome and celiac disease.

**Synonyms:** - ABC Transporter, MHC 1 Gene - ABC Transporter, MHC, 1 Gene - ABC17 - ABCB2 - APT1 - ATP-Binding Cassette Transporter, Major Histocompatibility Complex, 1 Gene - ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 2 Gene - ATP-Binding Cassette, Sub-Family B, Member 2 Gene - ATP-Binding Cassette, Subfamily B, Member 2 Gene - D6S114E - PSF-1 - PSF1 - RING4 - Really Interesting New Gene 4 - TAP1 - TAP1*0102N - TAP1N - Transporter 1, ATP-Binding Cassette, Sub-Family B (MDR/TAP) wt Allele - Transporter, ATP-Binding Cassette, Major Histocompatibility Complex, 1 Gene - Y3