TAP2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TAP2 wild-type allele is located in the vicinity of 6p21.3 and is approximately 9 kb in length. This allele, which encodes antigen peptide transporter 1 protein, plays a role in the modulation of the conformation and the activity of major histocompatibiltiy complex class I proteins. Mutations in this gene are associated with bare lymphocyte syndrome and rheumatoid arthritis.

**Synonyms:** - ABC Transporter, MHC 2 Gene - ABC Transporter, MHC, 2 Gene - ABC18 - ABCB3 - APT2 - ATP-Binding Cassette Transporter, Major Histocompatibility Complex, 2 Gene - ATP-Binding Cassette, Subfamily B, Member 3 Gene - D6S217E - PSF-2 - PSF2 - RING11 - Really Interesting New Gene 11 - TAP2 - Transporter 2, ABC (ATP Binding Cassette) Gene - Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) wt Allele - Transporter 2, ATP-Binding Cassette, Sub-Family B Gene - Transporter, ATP-Binding Cassette, Major Histocompatibility Complex, 2 Gene - Y1