CYP19A1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CYP19A1 wild-type allele is located in the vicinity of 15q21.2 and is approximately 131 kb in length. This allele, which encodes aromatase protein, is involved in the biosynthesis of estrogen. Certain allelic variants of the CYP19A1 gene exhibit functional mutations that result in enhanced aromatase activity which, in turn, causes familial gynecomastia.

**Synonyms:** - ARO - ARO1 - CPV1 - CYAR - CYP19 - CYPXIX - Cytochrome P450 Family 19 Subfamily A Member 1 wt Allele - Cytochrome P450, Family 19, Subfamily A, Polypeptide 1 Gene - Cytochrome P450, Subfamily XIX (Aromatization of Androgens) Gene - Cytochrome P450, Subfamily XIX Gene - P-450AROM