CYP2C8 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human CYP2C8 wild-type allele is located in the vicinity of 10q23.33 and is approximately 33 kb in length. This allele, which encodes cytochrome P450 2C8 protein, plays a role in the metabolism of drugs and xenobiotics. Several allelic variants of the CYP2C8 gene contribute to the poor metabolizer phenotype.

**Synonyms:** - CPC8 - Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 wt Allele - P450 MP-12/MP-20