AGT wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human AGT wild-type allele is located within 1q42-q43 and is approximately 12 kb in length. This allele, which encodes angiotensinogen protein, plays a role in the modulation of blood pressure. Mutations in the gene may increase the risk of essential hypertension, renal failure and preeclampsia.

**Synonyms:** - AGT - ANHU - Alpha-1 Antiproteinase, Antitrypsin Gene - Angiotensinogen (Serine (Or Cysteine) Proteinase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 8) Gene - Angiotensinogen wt Allele - Fetal-Liver Predominant Transporter 1 Gene - SERPINA8 - Serpin Peptidase Inhibitor, Clade A, Member 8 Gene - hFLT1