SMAD7 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SMAD7 wild-type allele is located in the vicinity of 18q21.1 and is approximately 31 kb in length. This allele, which encodes mothers against decapentaplegic homolog 7 protein, is involved in the attenuation of tumor growth factor-beta type 1 receptor signal transduction.

**Synonyms:** - CRCS3 - MAD (Mothers Against Decapentaplegic, Drosophila) Homolog 7 Gene - MAD, Mothers Against Decapentaplegic Homolog 7 (Drosophila) Gene - MADH7 - MADH7 Gene - MADH8 - Mothers Against Decapentaplegic, Drosophila, Homolog of, 7 Gene - SMAD Family Member 7 wt Allele - SMAD, Mothers Against DPP Homolog 7 (Drosophila) Gene - SMAD, Mothers Against DPP Homolog 7 Gene