COL4A3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human COL4A3 wild-type allele is located within 2q36.3 and is approximately 150 kb in length. This allele, which encodes collagen alpha-3 (IV) chain protein, is involved in the maintenance of the structure of the basement membrane. Mutation of the gene is linked to an autosomal recessive form of Alport syndrome.

**Synonyms:** - Alpha 3 Type IV Collagen Precursor Gene - COL4A3 - Collagen IV, Alpha-3 Polypeptide Gene - Collagen Type IV Alpha 3 Chain wt Allele - Collagen of Basement Membrane, Alpha-3 Chain Gene - Collagen, Type IV, Alpha 3 (Goodpasture Antigen) Gene - Collagen, Type IV, Alpha-3 Gene - Goodpasture Antigen Gene - TUMSTATIN Gene