H2AX wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human H2AX wild-type allele is located within 11q23.2-q23.3 and is approximately 2 kb in length. This allele, which encodes histone H2AX protein, is involved in the modulation of transcription, DNA replication and chromosomal stability. The allele may play a role in the regulation of both immunoglobulin class switch recombination and DNA double strand break repair.

**Synonyms:** - H2A Histone Family Member X Gene - H2A Histone Family, Member X Gene - H2A.X - H2A.X Variant Histone wt Allele - H2A/X - H2AFX - H2AFX wt Allele