AFF4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human AFF4 wild-type allele is located in the vicinity of 5q31 and is approximately 88 kb in length. This allele, which encodes AF4/FMR2 family member 4 protein, is involved in transcriptional regulation. A chromosomal aberration involving this gene and the MLL gene, insertion ins(5;11)(q31;q13q23), is associated with acute lymphoblastic leukemia.

**Synonyms:** - AF4/FMR2 Family Member 4 wt Allele - AF4/FMR2 Family, Member 4 Gene - AF5Q31 - AF5Q31 Gene - ALL1 Fused Gene From 5q31 Gene - CHOPS - HSPC092 - MCEF