ARNT wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ARNT wild-type allele is located in the vicinity of 1q21 and is approximately 67 kb in length. This allele, which encodes aryl hydrocarbon receptor nuclear translocator protein, plays a role in the modulation of the transcriptional response to halogenated aromatic hydrocarbons. This gene and the ETV6 gene are involved in a translocation t(1;12)(q21;p13) that is associated with acute myeloblastic leukemia.

**Synonyms:** - ARNT - Aryl Hydrocarbon Receptor Nuclear Translocator wt Allele - Dioxin Receptor, Nuclear Translocator Gene - HIF-1 Beta Gene - HIF-1-beta - HIF-1Beta Gene - HIF-1beta - HIF1-Beta Gene - HIF1B - HIF1B Gene - HIF1BETA - HIF1Beta - HIF1beta Gene - Hypoxia-Inducible Factor 1 Beta Gene - Hypoxia-Inducible Factor 1, Beta Subunit Gene - TANGO - bHLHe2